Find Relief with SPRAVATO® at Psychiatric Wellness Center
Cycling through medications can be frustrating and exhausting. If you have tried two or more antidepressants without finding relief, you are not alone—and there is another way. Discover SPRAVATO® (esketamine), an FDA-approved prescription nasal spray for Treatment-Resistant Depression (TRD), administered safely under the supervision of our compassionate medical team.
What is SPRAVATO®?
SPRAVATO® (esketamine) CIII is a prescription nasal spray used alongside an oral antidepressant to treat adults with Treatment-Resistant Depression (TRD) and depressive symptoms in adults with Major Depressive Disorder (MDD) accompanied by suicidal thoughts or actions. It is believed to work differently than traditional antidepressants, targeting a different receptor in the brain to help you begin to feel like yourself again.
Who is SPRAVATO® For?
Clinical depression is one of the most common mental health disorders, but standard treatments don’t work for everyone. You might be a candidate for SPRAVATO® if:
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You are an adult diagnosed with Major Depressive Disorder.
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You have tried at least two different oral antidepressants, and they have not provided adequate relief (Treatment-Resistant Depression).
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You are looking for a supervised, innovative approach to achieving psychiatric wellness.
How Taking SPRAVATO® Works
Because of the potential for temporary side effects like sedation and dissociation, SPRAVATO® is never taken at home. Here is what your treatment day at Psychiatric Wellness Center will look like:
Administering: You will self-administer the nasal spray under the direct supervision of our trained healthcare providers.
Observation: You will relax in our comfortable, private clinic space while our staff monitors you for at least two hours to ensure your safety and comfort.
Heading Home: Because SPRAVATO® can cause sleepiness or a feeling of disconnect, you cannot drive or operate machinery until the next day following a restful sleep. You will need to plan for a friend, family member, or caregiver to drive you home.
Why Choose Psychiatric Wellness Center for Treatment?
SPRAVATO® is only available through a restricted program called the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS). Psychiatric Wellness Center is a certified healthcare setting, meaning our specialized clinicians are fully trained to administer this medication and monitor your safety. From our Bakersfield offices to our San Diego care hub, we take a “Whole Person Care” approach to ensure you are supported before, during, and after your treatments.
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Spravato Teatment
How often do I need Spravato?
Phase 1 (Induction): In weeks 1-4 patients are required to administer the medication within the approved medical facility and be monitored for a minimum of 2 hours twice a week.
Phase 2 (Maintenance): Weeks 5-8 patients come once weekly, and continued medical observation requirements remain.
Phase 3 (Ongoing Treatment): Patients follow up every 2 weeks for administration and require observation during the single treatment.
What are the side effects of Spravato?
During the Spravato treatment, we will maintain a relaxing environment while we monitor based on the requirements set before us. Commonly, patients may experience mild disassociation and elevated blood pressure. As a controlled substance, this medication does carry a risk of dependence. We encourage all patients who consider using Spravato to ensure they are under the observation of a specialist.
Additional side effects may include:
- Fatigue
- Dissociation (Feeling disconnected from your body)
- Increased blood pressure
- Difficulty concentrating and dizziness
- Inability to drive or operate machinery
- Suicidal thoughts for young adults
Fatigue
Will SPRAVATO® replace my current medication?
No. SPRAVATO® is designed to be taken in conjunction with a daily oral antidepressant, not as a standalone replacement. Our providers will help manage your medications to ensure the safest and most effective results.
Is SPRAVATO® covered by insurance?
SPRAVATO® is covered by many major insurance plans. At Psychiatric Wellness Center, we accept most major private insurances and Medicare. Our team can help you navigate your insurance benefits and the SPRAVATO® withMe Patient Support Program to explore cost-support options.
How do I know if I have Treatment-Resistant Depression (TRD)?
If you have taken two or more antidepressants of adequate dose and duration and they haven’t worked well for you, you may have TRD. Schedule an evaluation with our providers to discuss your medical history and determine if SPRAVATO® is the right next step.
IMPORTANT SAFETY INFORMATION: SPRAVATO® can cause serious side effects, including sedation, dissociation, and respiratory depression. You will be monitored by a healthcare provider for at least 2 hours after administration. There is a risk of abuse and misuse, leading to physical and psychological dependence. SPRAVATO® may increase suicidal thoughts and actions in some people 24 years of age and younger. Tell your provider right away if you have sudden changes in mood or behavior. Do not take SPRAVATO® if you have a history of bleeding in the brain or certain blood vessel diseases.
Please discuss the full Prescribing Information, including Boxed WARNINGS, with your Psychiatric Wellness Center provider.
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